Paola Signorelli Selected Research

Proteins (Proteins, Gene)

6/2021	Inhibition of Ceramide Synthesis Reduces α-Synuclein Proteinopathy in a Cellular Model of Parkinson's Disease.
1/2020	Inhibition of Sphingolipid Synthesis as a Phenotype-Modifying Therapy in Cystic Fibrosis.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Paola Signorelli Research Topics

Disease

12	Inflammation (Inflammations) 01/2022 - 01/2014
7	Cystic Fibrosis (Mucoviscidosis) 01/2021 - 01/2014
7	Infections 01/2021 - 01/2014
6	Neoplasms (Cancer) 10/2015 - 08/2005
4	Pneumonia (Pneumonitis) 01/2020 - 01/2015
4	Chronic Obstructive Pulmonary Disease (COPD) 08/2017 - 01/2015
3	Parkinson Disease (Parkinson's Disease) 06/2021 - 07/2020
3	Proteostasis Deficiencies 06/2021 - 01/2020
3	Breast Neoplasms (Breast Cancer) 11/2010 - 12/2003
2	Reperfusion Injury 01/2019 - 03/2016
2	Ischemia 01/2019 - 03/2016
2	Necrosis 01/2019 - 03/2016
2	Carcinogenesis 10/2015 - 08/2005
2	Stomach Neoplasms (Stomach Cancer) 10/2015 - 09/2009
1	Chronic Renal Insufficiency 01/2022
1	Dyslipidemias (Dyslipidemia) 01/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2020
1	Myocardial Infarction 01/2019
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2019
1	Infarction (Infarctions) 01/2019
1	Emphysema 08/2017
1	Retinal Degeneration 07/2017
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 07/2017
1	Mycoses (Diseases, Fungus) 06/2016
1	Myocardial Reperfusion Injury 03/2016
1	Coronary Occlusion 03/2016
1	Aspergillosis 10/2015
1	Acute Lung Injury 01/2015
1	Colonic Neoplasms (Colon Cancer) 02/2014
1	Communicable Diseases (Infectious Diseases) 01/2014
1	Carcinoma (Carcinomatosis) 12/2012
1	Mitochondrial Diseases (Mitochondrial Disease) 10/2002

Drug/Important Bio-Agent (IBA)

15	SphingolipidsIBA 01/2021 - 01/2005
11	CeramidesIBA 06/2021 - 12/2003
9	LipidsIBA 06/2021 - 01/2014
8	thermozymocidin (myriocin)IBA 01/2021 - 01/2014
4	ResveratrolIBA 10/2015 - 12/2003
3	EnzymesIBA 01/2021 - 08/2005
3	AntioxidantsIBA 01/2020 - 01/2015
2	Proteins (Proteins, Gene)FDA Link 06/2021 - 01/2020
2	CholesterolIBA 01/2021 - 01/2020
2	Phenylalanine (L-Phenylalanine)FDA Link 01/2020 - 01/2020
2	dihydroceramideIBA 12/2012 - 09/2009
1	CurcuminIBA 01/2022
1	SynucleinsIBA 06/2021
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2021
1	Triglycerides (Triacylglycerol)IBA 01/2021
1	SphingomyelinsIBA 01/2021
1	Biomarkers (Surrogate Marker)IBA 12/2020
1	Cholesterol Esters (Cholesteryl Esters)IBA 12/2020
1	Phospholipids (Phosphatides)FDA LinkGeneric 12/2020
1	Ether (Diethyl Ether)IBA 12/2020
1	SugarsIBA 07/2020
1	Therapeutic UsesIBA 01/2020
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2020
1	Histones (Histone)IBA 01/2020
1	We 201IBA 08/2017
1	Chloride Channels (Chloride Channel)IBA 08/2017
1	SmokeIBA 07/2017
1	CytokinesIBA 07/2017
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 07/2017
1	Interleukin-6 (Interleukin 6)IBA 01/2016
1	Serine (L-Serine)FDA Link 01/2016
1	TransferasesIBA 01/2016
1	Surface-Active Agents (Surfactants)IBA 01/2015
1	Transcription Factors (Transcription Factor)IBA 02/2014
1	Etoposide (VP 16)FDA LinkGeneric 12/2012
1	dihydroceramide desaturaseIBA 12/2012
1	DNA (Deoxyribonucleic Acid)IBA 11/2010
1	Biological ProductsIBA 08/2005
1	Nitric Oxide Synthase (NO Synthase)IBA 08/2005
1	Mitogen-Activated Protein KinasesIBA 08/2005
1	Phosphotransferases (Kinase)IBA 08/2005
1	Tyrosine (L-Tyrosine)FDA Link 08/2005
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 08/2005
1	PolyphenolsIBA 08/2005
1	Caspase 9IBA 10/2002
1	Cytochromes c (Cytochrome c)IBA 10/2002

Therapy/Procedure

3	Therapeutics 01/2020 - 10/2015
2	Drug Therapy (Chemotherapy) 10/2015 - 01/2015
1	Thrombolytic Therapy 01/2019
1	Percutaneous Coronary Intervention 01/2019
1	Radiotherapy 10/2015
1	Canes (Cane) 05/2008